Lipid -Lowering Effect of Polysaccharide (Pectin) of Viscum album L. Plant in Rats

Disturbances of lipid metabolism is a predisposing factor cardiovascular diseases, which are accompanied by high mortality rates the population - ischemic heart disease and stroke. Plant polysaccharides can be promising remedies for correction imbalance.
 In this regard, aim study was to assess hypolipidemic activity isolated from leaves mistletoe.
 The test-object white mistletoe (Viscum album L.) growing on apple (Malus domestica Borkh.), pear (Pyrus communis L.). Polysaccharides (water-soluble pectin substances) were quantitatively determined gravimetric method followed reprecipitation ethanol. qualitative composition evaluated thin layer chromatography. Functional groups in titrimetric method. obtained under oral administration at dose 100 mg / kg Wistar rats change concentration total cholesterol, triglycerides, LDL HDL cholesterol. content cholesteryl ester transfer protein Niemann-Pick C1-Like1 also determined.
 As result, it found that among mistletoe, substances predominate, belong group low-esterified pectins. A significant free carboxyl pectins found. showed that, leaves, exert more pronounced effect metabolism, use reduced cholesterol with an increase rats, probably due decrease protein. At same time, level trend, higher than analogous compounds host-plants. It should noted severity pharmacological did not depend host-plants.
 Thus, based results, assumed potentially effective safety agent.